DIETHYL METHYLMALONATE

PRODUCT IDENTIFICATION
CAS NO. 609-08-5

DIETHYL METHYLMALONATE

EINECS NO. 210-175-7
FORMULA CH3CH(CO2C2H5)2
MOL WT. 174.20

H.S. CODE

 2917.19

TOXICITY

 Oral rat LD50: 5000 mg/kg
SYNONYMS Propanedioic acid, methyl-, diethyl ester;
Diethyl 2-methylpropanedioate; Methylmalonic acid diethyl ester; Diethyl 2-methylmalonate; Methylmalonic acid diethyl ester; Metilmalonato di dietile (Italian);   Methylmalonsäurediethylester (German); Méthylmalonate de diéthyle (French);
RAW MATERIALS

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE Clear liquid
MELTING POINT  
BOILING POINT

198 - 199 C

SPECIFIC GRAVITY

1.020 - 1.025

SOLUBILITY IN WATER Immiscible
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

1.412 - 1.414

NFPA RATINGS

  

AUTOIGNITION

 

FLASH POINT

85 C

STABILITY Stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS
Malonic acid (also called Propanedioic Acid ) is a white crystalline C-3 dicarboxylic acid; melting at 135 -136 C; readily soluble in water, alcohol and ether; solution in water is medium-strong acidic. It can be derived by oxidizing malic acid or by the hydrolysis of cyanacetic acid. Malonic acid itself is rather unstable and has few applications. It's diethyl ester (diethyl malonate) is more important commercially. Diethyl malonate, a colourless, fragrant liquid boiling at 199 C, is prepared by the reaction of monochloroacetatic acid with methanol, carbon monoxide or by the reaction cyanoacetic acid (the half nitriled-malonic acid) with ethyl alcohol. Malonic acid and its esters contain active methylene groups which have relatively acidic alpha-protons due to H atoms adjacent to two carbonyl groups. The reactivity of its methylene group provide the sequence of reactions of alkylation, hydrolysis of the esters and decarboxylation resulting in substituted ketones. The methylene groups in 1,3-dicarboxylic acid utilize the synthesis of barbiturates; a hydrogen atom is removed by sodium ethoxide, and the derivative reacts with an alkyl halide to form a diethyl alkylmalonate. The diethyl dialkylmalonates are converted to barbiturates by reaction with urea. Malonic acid and its esters are characterized by the large number of condensation products. They are important intermediates in syntheses of vitamins B1 and B6, barbiturates, non-steroidal anti-inflammatory agents, other numerous pharmaceuticals, agrochemicals and flavors & fragrances compounds.
SALES SPECIFICATION

APPEARANCE

 Clear liquid

ASSAY (G.C)

99.0% in

METHYLMALONIC ACID

 1.0% max

DIETHYL MALONATE

0.3% max
WATER

0.1% max

ETHANOL

0.1% max

TOLUENE

0.05% max

ETHYL PROPIONATE

0.3% max

ETHYL LACTATE

0.05% max

INDIVIDUAL IMPURITY

0.1% max
TRANSPORTATION
PACKING
200kgs in Drum
HAZARD CLASS  
UN NO.  
OTHER INFORMATION